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by Dirk J. Ruiter,G.J. Fleuren,S.O. Warnaar

  • ISBN: 0898388538
  • Category: Other
  • Author: Dirk J. Ruiter,G.J. Fleuren,S.O. Warnaar
  • Subcategory: Medicine & Health Sciences
  • Other formats: docx mbr doc mobi
  • Language: English
  • Publisher: Springer; 1987 edition (March 31, 1987)
  • Pages: 391 pages
  • FB2 size: 1602 kb
  • EPUB size: 1217 kb
  • Rating: 4.6
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Download Application of Monoclonal Antibodies in Tumor Pathology (Developments in Oncology) fb2

The development of monoclonal antibodies to human tumor associated . Monoclonal Antibodies in Breast Tumor Pathology. Monoclonal Antibodies Reacting with Tumors of the Urological Tract or Prostate. Warnaar, S. O. (et a.

The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. Monoclonal Antibodies in Clinical and Experimental Pathology of Lung Cancer.

cle{osti 7192123, title {Application of monoclonal antibodies in tumor pathology}, author {Ruiter, . abstractNote {This book contains papers under the following three section headings: Basic and technical aspects; Tumor associated antigens; and Practical application and case presentations. Monoclonal antibodies in the treatment of cancer. Journal Article Dillman, .

Fleuren; . Поставляется из: Германии Описание: The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application o. .

Application of Monoclonal Antibodies in Tumor Pathology Dirk J. Ruiter; . Поставляется из: Германии Описание: The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. Phenotypes of tumor cells have been identified which correlate with the biology of tumor cells and with the clinical course of the disease.

Application of Monoclonal Antibodies in Tumor Pathology (Developments. 1 2 3 4 5. Want to Read. Are you sure you want to remove Application of Monoclonal Antibodies in Tumor Pathology (Developments in Oncology) from your list? Application of Monoclonal Antibodies in Tumor Pathology (Developments in Oncology). Published December 31, 1899 by Springer.

Series Statement: Developments in oncology ; DION 50. General Note: "Based upon a Boerhaave course organized by the Faculty of Medicine, University of Leiden, the Netherlands in.Personal Name: Fleuren, Gert Jan. General Note: "Based upon a Boerhaave course organized by the Faculty of Medicine, University of Leiden, the Netherlands in cooperation with the Pathological Society of the Netherlands (NPAV) and the Comprehensive Cancer Centre West (IKW), the Netherlands" . General Note: Course held in Leiden in Jan. 1986.

Monoclonal antibodies in immunodiagnosis and immunotherapy of human cancer.

November 1985 · Nederlands tijdschrift voor geneeskunde. Monoclonal antibody (MAB) in patients with advanced cancer. March 2003 · Current Urology Reports. Hyung L Kim. Allan J Pantuck. Monoclonal antibodies in immunodiagnosis and immunotherapy of human cancer. March 1988 · European Journal of Surgical Oncology.

Monoclonal antibodies have become an important new class of therapeutic agents approved for use in solid tumors. They function through several different mechanisms including inhibition of tumor-related signal transduction, induction of apoptosis, inhibition of angiogenesis, enhancing host immune response against cancer and targeted delivery of cytotoxic agents to the tumor site.

Application of Monoclonal Antibodies in Tumor Pathology. Dirk J. Ruiter, Gert Jan Fleuren, S. Ole Warnaar. Characterization of two human small cell lung carcinoma-reactive monoclonal antibodies generated by a novel immunization approach. Alex W. Tong, Jae Lee, Marvin J. Stone. Developments in Oncology. Immunology of Malignant Diseases. Sanford O. Byers, Wendy Baldwin. Immunology and Medicine. Heterogeneous expression of cell-surface antigens in normal epithelia and their tumours, revealed by monoclonal antibodies. British Journal of Cancer.

Series: Developments in Oncology 49. File: PDF, 1. 7 MB. Читать онлайн. Application of Monoclonal Antibodies in Tumor Pathology. Ruiter, Gert Jan Fleuren, Sven O. Warnaar (ed. Год: 1987. File: PDF, . 6 MB. 2. Anesthesia, The Heart and the Vascular System: Annual Utah Postgraduate Course in Anesthesiology 1987.

In oncology drug development, quantitative data supporting MoA elucidation are typically generated at the preclinical stage.

Historical milestones include adaptations of the Gompertz model for treatment outcomes in breast cancer (16) In oncology drug development, quantitative data supporting MoA elucidation are typically generated at the preclinical stage.

The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. During the last few years this approach has been utilized by a progressively increasing number of investigators to analyze malignant cells. Although monoclonal antibodies to tumor associated antigens have not become yet routine reagents in immunopathology, they have provided new information which could not be obtained with conventional antisera or histochemical procedures. The following are representative examples. TUmor associated antigens have been identified which display a restricted distribution in normal tissues and therefore may represent useful markers for radio­ imaging and appropriate targets for immunotherapy. In spite of undetec­ table differences with conventional histopathological approaches hetero­ geneity has been found in the antigenic profile of tumor cells within a lesion, in autologous lesions removed from different anatomic sites from a given patient and in lesions removed from different patients. Phenotypes of tumor cells have been identified which correlate with the biology of tumor cells and with the clinical course of the disease. From a practical view point the use of monoclonal antibodies in immunopathology has enhanced interactions between pathologists and immunologists, as exemplified by the present book. Such interactions have contributed to the application of basic research to clinical problems. The chapter of this book discuss investigations performed with monoclonal antibodies to antigens expressed by various types of normal and malignant human cells.

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