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by Scott H. Podolsky

  • ISBN: 0674001826
  • Category: Other
  • Author: Scott H. Podolsky
  • Subcategory: Medicine & Health Sciences
  • Other formats: doc azw rtf mbr
  • Language: English
  • Publisher: Harvard University Press (May 5, 2000)
  • Pages: 528 pages
  • FB2 size: 1395 kb
  • EPUB size: 1585 kb
  • Rating: 4.8
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Download The Generation of Diversity: Clonal Selection Theory and the Rise of Molecular Immunology fb2

Clonal selection theory is a scientific theory in immunology that explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body.

Clonal selection theory is a scientific theory in immunology that explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body. The concept was introduced by Australian doctor Frank Macfarlane Burnet in 1957, in an attempt to explain the great diversity of antibodies formed during initiation of the immune response

The clonal selection theory explains that cells with genetic instructions to. .The Generation of Diversity is an intellectual history of the major.

The clonal selection theory explains that cells with genetic instructions to produce each antibody exist in the body in small numbers until exposure to the right molecule-the antigen-triggers the selective cloning that will reproduce exactly the cell needed. The solution to this question came from new applications of molecular biology, and, as the authors argue, the impact of the new techniques changed both the methods and the concepts of immunology. The Generation of Diversity is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period.

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Scott H Podolsky, Alfred I Tauber, The generation ofdiversity: clonal selection theory and the rise of molecular immunology, Cambridge, Mass. and London, Harvard University Press, 1997, pp. x, 508, £4. 5 (0-674-77181-8). Volume 43, Issue 3. Ilana Löwy (a1). By using this service, you agree that you will only keep articles for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services. Please confirm that you accept the terms of use. Cancel. Send article to Dropbox.

Immunology by Scott H. Podolsky; Alfred I. Tauber Metchnikoff and the Origins of Immunology: From Metaphor to Theory by.Theory Change in Immunology Part II: The Clonal Selection Theory

The Generation of Diversity: Clonal Election Theory and the Rise of Molecular Immunology by Scott H. Tauber. Jean-Paul Gaudilliere. Isis: A Journal of the History of Science 92:233-234 (2001). Metchnikoff and the Origins of Immunology: From Metaphor to Theory by Alfred I. Tauber; Leon Chernyak. Pauline Mazumdar - 1992 - Isis: A Journal of the History of Science 83:504-505. Theory Change in Immunology Part II: The Clonal Selection Theory. Kenneth F. Schaffner - 1992 - Theoretical Medicine and Bioethics 13 (2). Expanding Immunology: Defensive Versus Ecological Perspectives.

The book explores clonal selection theory, its explanation of genetic . F. Scott Fitzgerald Paperback General & Literary Fiction Books in Spanish.

The book explores clonal selection theory, its explanation of genetic instructions in cells and looks at the impact of new techniques. Scott H. Podolsky is a First-Year Resident in Medicine at Brigham and Women's Hospital in Boston. Alfred I. Tauber is Professor of Medicine and Philosophy and Director at the Center for Philosophy and History of Science, Boston University. Classics Paperback F. Scott Fitzgerald General & Literary Fiction Books.

The Generation of Diversity book. Goodreads helps you keep track of books you want to read

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In recent decades immunology has been one of the most exciting--and successful--fields of biomedical research. Over the past thirty years immunologists have acquired a detailed understanding of the immune system's unique recognition mechanism and of the cellular and chemical means used to destroy or neutralize invading organisms. This understanding has been formulated in terms of the clonal selection theory, the dominant explanation of immune behavior. That story is the subject of The Generation of Diversity.

A major problem for immunologists had long been to determine how cells of the immune system could produce millions of distinct antibodies--and produce them on demand. The clonal selection theory explains that cells with genetic instructions to produce each antibody exist in the body in small numbers until exposure to the right molecule--the antigen--triggers the selective cloning that will reproduce exactly the cell needed. But how can so many different antibody-producing cells be generated from such limited genetic material? The solution to this question came from new applications of molecular biology, and, as the authors argue, the impact of the new techniques changed both the methods and the concepts of immunology.

The Generation of Diversity is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. It will provide for immunologists essential background for understanding the conceptual conflicts occurring in the field today.



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