» » Concerning the Origin of Malignant Tumours

Download Concerning the Origin of Malignant Tumours fb2

by Theodor Boveri

  • ISBN: 0879697881
  • Category: Other
  • Author: Theodor Boveri
  • Subcategory: Medicine & Health Sciences
  • Other formats: mbr docx txt azw
  • Language: English
  • Publisher: Cold Spring Harbor Laboratory Press; 1 edition (January 18, 2008)
  • Pages: 100 pages
  • FB2 size: 1904 kb
  • EPUB size: 1400 kb
  • Rating: 4.6
  • Votes: 769
Download Concerning the Origin of Malignant Tumours fb2

Boveri also discovered the phenomenon of chromatin diminution during embryonic development of the nematode Parascaris. Boveri, Theodor (2008). Concerning The Origin of Malignant Tumours".

Boveri also discovered the phenomenon of chromatin diminution during embryonic development of the nematode Parascaris. He also reasoned in 1902 that a cancerous tumor begins with a single cell in which the makeup of its chromosomes becomes scrambled, causing the cells to divide uncontrollably. He proposed carcinogenesis was the result of aberrant mitoses and uncontrolled growth caused by radiation, physical or chemical insults or by microscopic pathogens. Journal of Cell Science. 121 (Supplement 1): 1–84.

Concerning the Origin o. .has been added to your Cart. What makes Boveri s writing worth reading almost a century later is his ability to distil complex information, including the ideas and observations of others, into brilliant, incisive syntheses

Concerning the Origin o. What makes Boveri s writing worth reading almost a century later is his ability to distil complex information, including the ideas and observations of others, into brilliant, incisive syntheses. For those biologists among us who are interested in how we got to where we are, this book makes fascinating reading, even if it does not lay down an accurate trail of previous discoveries.

My knowledge comes almost exclusively from books I shall discuss later how I regard the origin of tumours that are produced by physical or chemical agents.

My knowledge comes almost exclusively from books. Given this, it is inevitable that I am unaware of many reports in the literature, that I overestimate the significance of many known facts and that I do not set enough store by others. A malignant tumour cell is – and here again I take up the ideas of Hansemann – a cell with a specific abnormal chromosome constitution. Although this assumption cannot be elaborated more precisely, there are some observations that might nonetheless be relevant. Estimates of the number of chromosomes in man vary widely. I shall discuss later how I regard the origin of tumours that are produced by physical or chemical agents.

Start by marking Concerning the Origins of Malignant Tumours as Want to Read .

Start by marking Concerning the Origins of Malignant Tumours as Want to Read: Want to Read savin. ant to Read. In it he argues that malignancy arises as a consequence of chromosomal abnormalities and that multiplication is an inherent property of An English translation of Boveri's famous monograph which was first published in Germany in 1914.

Translated and annotated by Henry Harris. University of Würzburg. Journal Journal of Cell Science. Volume 121 Suppl 1. Pages 1-84. Publication Date 1 January 2008. Publication metadata is provided by PubMed®, a database of the . National Library of Medicine. Information for this publication was last updated on 19 September 2019.

4. malignant tumours. 4. concerning origin. Press proceed to send the authors a message. Thank You. We have submitted your request - we will update you on status within the next 48 hours.

Concerning The Origin of Malignant Tumours".

This discovery was an important part of the Boveri–Sutton chromosome theory. His other significant discovery was the centrosome (1888), which he described as the especial organ of cell division. Boveri also discovered the phenomenon of chromatin diminution during embryonic development of the nematode Parascaris.

Concerning the origin of malignant tumours by Theodor Boveri. Meiosis was studied in seven tetraploid (2n 4x 28) wheat (Triticum turgidum . landrace morphotypes of Ethiopian origin and one introduced durum variety, ‘Boohai’

Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris. landrace morphotypes of Ethiopian origin and one introduced durum variety, ‘Boohai’. The objectives were to detect the presence of chromosome structural rearrangements by using the variety ‘Senatore Cappelli’ (SC) as a reference and to investigate if the previously reported low fertility (seed set) of the landraces.

Boveri, Theodor (2008). Maderspacher, Florian (2008). Theodor Boveri and the natural experiment". Current Biology 18 (7): R279–R286. Satzinger, Helga (March 2008). Laubichler, Manfred D; Davidson Eric H (February 2008). Boveri's long experiment: Sea urchin merogones and the establishment of the role of nuclear chromosomes in development". Bignold, Leon P; Coghlan Brian L D, Jersmann Hubertus P A (July 2006)

An English translation of Boveri's famous monograph which was first published in Germany in 1914. Written almost a hundred years ago, Theodor Boveri's Zur Frage der Entstehung maligner Tumoren has had a momentous impact on cancer research. In it he argues that malignancy arises as a consequence of chromosomal abnormalities and that multiplication is an inherent property of cells. With astonishing prescience, Boveri predicts in this monograph the existence of tumor suppressor mechanisms and is perhaps the first to suggest that hereditary factors (genes) are linearly arranged along chromosomes. This new translation by Sir Henry Harris, Regius Professor of Medicine Emeritus at Oxford University and former Editor-in-Chief of Journal of Cell Science, includes extensive annotations in which he discusses the relevance of Boveri's views today. It is essential reading for all cancer researchers, as well as those interested in the history of cytogenetics and cell biology.

Related to Concerning the Origin of Malignant Tumours fb2 books: