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by Valentin Fuster

  • ISBN: 0879934069
  • Category: Medical Books
  • Author: Valentin Fuster
  • Subcategory: Medicine
  • Other formats: rtf lrf docx doc
  • Language: English
  • Publisher: Wiley-Blackwell; 1 edition (January 15, 1999)
  • Pages: 429 pages
  • FB2 size: 1224 kb
  • EPUB size: 1666 kb
  • Rating: 4.7
  • Votes: 406
Download The Vulnerable Atherosclerotic Plaque: Understanding, Identifi- cation and Modification fb2

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Public Health Atherosclerotic Plaque Vulnerable Atherosclerotic Plaque. Authors and Affiliations. 1. merican Heart Association, Monograph SeriesFutura Publishing Company, Inc, 1998Armonk. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This monograph is a valuable multidisciplinary resource, written by experts in the fields of mechanical and electrical engineering, pathology, neurology, imaging, clinical and vascular biology, physics, radiology and surgery.

Atherothrombosis and Coronary Artery Disease by Valentin Fuster, Eric J. Topol and Elizabeth G. Nabel (Nov 8. . Nabel (Nov 8, 2004).

Valentin Fuster MD, PhD. ISBN: 9780879934064; In the late 1950s, atherosclerotic lesions in the arteries were intensely scrutinised at autopsy by the Committee on Vascular Lesions, a creative forum that became part of the American Heart Association in 1959. By the early 1980s, concerned efforts brought many medical subspecialties together to quantify treatments of atherosclerosis in the living, by comparing results and standardising on measurements and terms deployed

provides a particularly comprehensive and timely over-view. Equal space is given to the investigations into mechanical wall stress/strain, flow dynamics, and theol-ogy as they relate to the vulnerable plaque and throm-bosis.

provides a particularly comprehensive and timely over-view. In summary, a detailed yet tolerable overview of the current concepts related to atherosclerotic disease and plaque rupture is presented. Chapters are well written, concise, and contain extensive reference sections for those who want to proceed with a more intense scrutiny of a particular topic

The stages in the overall atherosclerotic plaque process appear to be (a) adhesion of monocytes (essentially, larger particulate suspensions) to the endothelial surface, which is controlled by the adhesion molecules stimulated by the excess LDL, the oxygen content and the intensity of the blood flow; (b) penetration of the monocytes into the intima and subsequent inflammation of the tissue; and (c) rupture of. the plaque accompanied by some degree of thrombus formation or even subsequent occlusive thrombosis.

The Vulnerable Atherosclerotic Plaque: Understanding, Identification and Modification Valentin Fuster .

After a considered and concise ntroduction, the book concentrates on: Pathology of vulnerable plaque; Triggers for plaque rupture; Imaging of unstable plaque; and, Management of vulnerable plaques.

The atherosclerotic plaque. In: Fuster V, ed. The vulnerable atherosclerotic plaque: understanding, identification, and modification. New York: Futura Publishing; 1999:213�29. Atherosclerosis begins as a subendothelial accumulation of lipid laden, monocyte derived foam cells and associated T cells which form a non-stenotic fatty streak. With progression, the lesions take the form of an acellular core of cholesterol esters bounded by an endothelialised fibrous cap containing vascular smooth muscle cells (VSMC) and inflammatory cells, predominantly macrophages with some T cells and mast cells, which tend to accumulate at the shoulder regions of the plaque.

In the late 1950s, atherosclerotic lesions in the arteries were intensely scrutinised at autopsy by the Committee on Vascular Lesions, a creative forum that became part of the American Heart Association in 1959. By the early 1980s, concerned efforts brought many medical subspecialties together to quantify treatments of atherosclerosis in the living, by comparing results and standardising on measurements and terms deployed. With improved understandings about the vascular wall, the Committee was able to develop a classification of atherosclerotic lesions.

This work reveals critical understandings about the natural history of plaque, the correlation of vascular lesions and clinical syndromes, and the utility of new imaging methods. Diagnostic imaging, atherosclerosis prevention and treatment will be shaped by these new modalities. Continuous scrutiny by the Committee is culminating in scientific meetings every few years, and is summarised in published statements. The present statement The Vulnerable Atherosclerotic Plaque: Understanding, Identification and Modification is the second of these documents to focus on atherosclerosis pathogenesis and pathological clinical implications.

As a multi-disciplinary resource, this book edited by Valentin Fuster, MD, PhD, chairman of the committee, consists of twenty four chapters written by experts in mechanical and electrical engineering, pathology, neurology, imaging, clinical and vascular biology, physics, radiology and surgery. This invaluable reference tool identifies problems, perspectives and critical new questions for evaluation and dissemination.



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