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by Gabriele Proetzel,Michael V. Wiles

  • ISBN: 1607610574
  • Category: Medical Books
  • Author: Gabriele Proetzel,Michael V. Wiles
  • Subcategory: Medicine
  • Other formats: doc lrf mobi lit
  • Language: English
  • Publisher: Humana Press; 2010 edition (December 17, 2009)
  • Pages: 421 pages
  • FB2 size: 1322 kb
  • EPUB size: 1657 kb
  • Rating: 4.3
  • Votes: 467
Download Mouse Models for Drug Discovery: Methods and Protocols (Methods in Molecular Biology) fb2

Methods and Protocols This book details methods for drug delivery and common measurements using . Profiling of Drug Action Using Reporter Mice and Molecular Imaging.

Methods and Protocols. Provides an excellent source for understanding the strength of the mouse as a model. This book details methods for drug delivery and common measurements using mouse and disease models.

Methods and Protocols Written for the highly successful Methods in Molecular Biology series . Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Show all. Table of contents (21 chapters).

Book · January 2010 with 7 Reads

Book · January 2010 with 7 Reads.

Mostly the data of the books and covers were damaged so many books are not .

Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Start by marking Mouse Models For Drug Discovery: Methods And .

Start by marking Mouse Models For Drug Discovery: Methods And Protocols (Methods In Molecular Biology) as Want to Read: Want to Read savin. ant to Read. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse.

As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to. .

As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. Written in the highly successful Methods in Molecular Biology(tm) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known.

Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

oceedings{Proetzel2010MouseMF, title {Mouse Models for Drug Discovery}, author {Gabriele Proetzel and Michael V. Wiles}, booktitle {Methods in Molecular Biology}, year {2010} }. Gabriele Proetzel, Michael V. Wiles. According to the US Food and Drugs Administration (Food and Drug Administration (2004) Challenge and opportunity on the critical path to new medical products. The inability to better assess and predict product safety leads to failures during clinical development and, occasionally, after marketing.

As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In Mouse Models for Drug Discovery: Methods and Protocols, experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easy-to-use, Mouse Models for Drug Discovery: Methods and Protocols will stimulate those not familiar with the power of the mouse and its potential for the drug discovery process, and it will encourage the development of new models and new ways to utilize existing models in order to further the use of this dynamic animal in this vital field.



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